JADA Foundational Science (JADA FS) is a cross-disciplinary, open access journal publishing original research articles and reviews on a broad range of topics in dental, oral, and craniofacial health. JADA FS provides a forum for researchers in basic and applied sciences to make their work visible to experts in clinical dentistry and medicine. The aim is to highlight foundational science, as well as new and emerging scientific ideas, tools, and techniques, as they are applied to research questions in oral and craniofacial health. Pertinent studies are invited in the areas of biology, chemistry, engineering, materials science, computer science and informatics, advanced imaging and processing, and other technologies. Our goal is to recruit timely and innovative work of high scientific rigor that is applicable to the field of oral and craniofacial health, presented in a way that is engaging and instructive to both research scientists and clinicians. JADA FS employs a double-blind peer review process.