Human Genetics and Genomics Advances is an open-access journal publishing across the complete spectrum of human genetic and genomic research. Its mission is to build the human genetics and genomics knowledge base. HGG Advances is a home for human genetics and genomics research characterized by high standards of scientific rigor, validity, and reproducibility. HGG Advances is an important addition to the American Society of Human Genetics family of journals. It offers researchers a home for a wide variety of research findings and formats and is committed to prompt dissemination of results through timely peer review, continuous online publication, and innovation in responding to the human genetics and genomics community’s needs as the field evolves.