Gastro Hep Advances is the newest peer-reviewed journal published by the American Gastroenterological Association (AGA), joining Gastroenterology, Clinical Gastroenterology and Hepatology (CGH), Cellular and Molecular Gastroenterology and Hepatology (CMGH), and Techniques and Innovations in Gastrointestinal Endoscopy (TIGE). Gastro Hep Advances is a broad-scope, online-only, open access journal that publishes papers on basic, clinical, and translational gastroenterology and hepatology. The open access model enables authors with funding mandates to have a high-quality home for their research.

In addition to full-length original research articles, the journal publishes comprehensive reviews as well as commentaries and editorials. A core objective is to publish papers cascaded from AGA's other journals that represent outstanding science and therefore qualify for publication in a journal supported by the AGA brand. Gastro Hep Advances also strongly encourages the submission of manuscripts not originally submitted to the other AGA journals. Gastro Hep Advances is less concerned with novelty and subjective perceptions of significance; its aim is to publish digestive disease research that is technically, ethically, and scientifically sound. Through its special sections, the journal also provides unique insights. Pearls from the Pros share clinical pearls of knowledge developed through years of practice. Climate Change in Digestive Disease is a timely, relevant feature that delves into the impact of climate change on gastroenterology and hepatology. Looking to the future, Gastro Hep Advances plans to launch a special section focusing on transitions at all career stages within the field.