Clinical Colorectal Cancer is devoted to manuscripts that focus on early detection/screening, diagnosis, prevention, and treatment of colorectal cancer and other GI cancers, including pancreatic, liver, gastric/gastroesophageal, biliary, and other gastrointestinal cancers. The major emphasis is on recent scientific developments and original peer-reviewed manuscripts. Specific areas of interest include original reports on clinical research and/or translational research and translational correlative science that is directly related to clinical trials, in all (multidisciplinary) therapeutic fields that relate to colorectal cancer and other GI cancers.

Further areas of interest include original research on drug sensitivity and resistance to cytotoxic agents, targeted therapies, immunotherapies, and other novel therapeutic approaches; pathology, (validated) predictive markers, and prognostic indicators; chemoprevention strategies; and integration of various therapeutic and multidisciplinary approaches. A much lower priority will be given to meta-analyses, pooled analyses, and real-world analyses unless the knowledge gained from such reports is significant and can be applied to clinical practice. In addition, unsolicited reviews are not encouraged unless there has been a discussion with the editor or deputy editors as the journal wants to ensure that reviews will provide real added value and true gain of knowledge.