Published quarterly, The American Journal of Preventive Cardiology is the official journal the American Society for Preventive Cardiology. It publishes articles in the areas of prevention research, teaching, practice and policy. Original research and reviews are published on epidemiology and clinical studies on risk factors, behavioral and pharmacologic interventions aimed at the primary and secondary prevention of cardiovascular diseases and related conditions, as well as the promotion of individual and community cardiovascular health.

The journal publishes both original research and review papers that address the key aspects of preventive cardiology, including the primary and secondary prevention of cardiovascular disease and related conditions including both behavioral (e.g., smoking, obesity, diet, and physical activity) and clinical (e.g., dyslipidemia, hypertension, and diabetes) aspects. Papers also address educational and other initiatives and methods aimed at improving the ability of cardiologists and healthcare professionals to provide effective clinical prevention and public health services. The journal also publishes guidelines and official policy statements from the Society, review articles, media reviews, and editorials. Finally, the journal periodically publishes special theme issues devoted to areas of current interest to the cardiac prevention community. Also included are editorials, readers' comments, and abstracts from the annual ASPC scientific sessions.