CJC Open is a vehicle for the international dissemination of new knowledge in cardiology and cardiovascular science, particularly serving as the major open access publication venue for Canadian cardiovascular medicine. The journal publishes original reports of clinical and basic research relevant to cardiovascular medicine as well as editorials, viewpoints, review articles, and case reports. Papers on health outcomes, health care and public policy issues, ethics, medical history, and study design, as well as letters to the editor, are welcomed.