Includes bibliographical references and index.

Machine generated contents note: 1. Basic Concepts Of Medical Instrumentation / John C. Webster -- 1.1. Terminology of Medicine and Medical Devices -- 1.2. Generalized Medical Instrumentation System -- 1.3. Alternative Operational Modes -- 1.4. Medical Measurement Constraints -- 1.5. Classifications of Biomedical Instruments -- 1.6. Interfering and Modifying Inputs -- 1.7. Compensation Techniques -- 1.8. Biostatistics -- 1.9. Generalized Static Characteristics -- 1.10. Generalized Dynamic Characteristics -- 1.11. Amplifiers and Signal Processing -- 1.12. Inverting Amplifiers -- 1.13. Noninverting Amplifiers -- 1.14. Differential Amplifiers -- 1.15. Comparators -- 1.16. Rectifiers -- 1.17. Logarithmic Amplifiers -- 1.18. Integrators -- 1.19. Differentiators -- 1.20. Active Filters -- 1.21. Frequency Response -- 1.22. Offset Voltage -- 1.23. Bias Current -- 1.24. Input and Output Resistance -- 1.25. Design Criteria -- 1.26. Commercial Medical Instrumentation Development Process -- 1.27. Regulation of Medical Devices -- Problems -- References -- 2. Basic Sensors And Principles / John C. Webster -- 2.1. Displacement Measurements -- 2.2. Resistive Sensors -- 2.3. Bridge Circuits -- 2.4. Inductive Sensors -- 2.5. Phase-Sensitive Demodulators -- 2.6. Capacitive Sensors -- 2.7. Piezoelectric Sensors -- 2.8. Accelerometer -- 2.9. Temperature Measurements -- 2.10. Thermocouples -- 2.11. Thermistors -- 2.12. Radiation Thermometry -- 2.13. Fiber-Optic Temperature Sensors -- 2.14. Optical Measurements -- 2.15. Radiation Sources -- 2.16. Geometrical and Fiber Optics -- 2.17. Optical Filters -- 2.18. Radiation Sensors -- 2.19. Optical Combinations -- Problems -- References -- 3. Microcontrollers In Medical Instrumentation / Amit J. Nimunkar -- 3.1. Basics of Microcontroller -- 3.2. Embedded Medical System -- 3.3. ECG-Based Embedded Medical System Example -- 3.4. Selection of a Microcontroller -- 3.5. IoT-Based Medical Devices -- Problems -- References -- 4. The Origin Of Biopotentials / John W. Clark Jr. -- 4.1. Electrical Activity of Excitable Cells -- 4.2. Volume Conductor Fields -- 4.3. Functional Organization of the Peripheral Nervous System -- 4.4. The Electroneurogram -- 4.5. The Electromyogram -- 4.6. The Electrocardiogram -- 4.7. The Electroretinogram -- 4.8. The Electroencephalogram -- 4.9. The Magnetoencephalogram -- Problems -- References -- 5. Biopotential Electrodes / Michael R. Neuman -- 5.1. The Electrode-Electrolyte Interface -- 5.2. Polarization -- 5.3. Polarizable and Nonpolarizable Electrodes -- 5.4. Electrode Behavior and Circuit Models -- 5.5. The Electrode-Skin Interface and Motion Artifact -- 5.6. Body-Surface Recording Electrodes -- 5.7. Internal Electrodes -- 5.8. Electrode Arrays -- 5.9. Microelectrodes -- 5.10. Electrodes for Electric Stimulation of Tissue -- 5.11. Practical Hints in Using Electrodes -- Problems -- References -- 6. Biopotential Amplifiers / Michael R. Neuman -- 6.1. Basic Requirements -- 6.2. The Electrocardiograph -- 6.3. Problems Frequently Encountered -- 6.4. Transient Protection -- 6.5. Common-Mode and Other Interference-Reduction Circuits -- 6.6. Amplifiers for Other Biopotential Signals -- 6.7. Example of a Biopotential Preamplifier -- 6.8. Other Biopotential Signal Processors -- 6.9. Cardiac Monitors -- 6.10. Biotelemetry -- Problems -- References -- 7. Blood Pressure And Sound / Robert A. Peura -- 7.1. Direct Measurements -- 7.2. Harmonic Analysis of Blood Pressure Waveforms -- 7.3. Dynamic Properties of Pressure-Measurement Systems -- 7.4. Measurement of System Response -- 7.5. Effects of System Parameters on Response -- 7.6. Bandwidth Requirements for Measuring Blood Pressure -- 7.7. Typical Pressure-Waveform Distortion -- 7.8. Systems for Measuring Venous Pressure -- 7.9. Heart Sounds -- 7.10. Phonocardiography -- 7.11. Cardiac Catheterization -- 7.12. Effects of Potential and Kinetic Energy on Pressure Measurements -- 7.13. Indirect Measurements of Blood Pressure -- 7.14. Tonometry -- Problems -- References -- 8. Measurement Of Flow And Volume Of Blood / John C. Webster -- 8.1. Indicator-Dilution Method that Uses Continuous Infusion -- 8.2. Indicator-Dilution Method that Uses Rapid Injection -- 8.3. Electromagnetic Flowmeters -- 8.4. Ultrasonic Flowmeters -- 8.5. Thermal-Convection Velocity Sensors -- 8.6. Chamber Plethysmography -- 8.7. Electrical-Impedance Plethysmography -- 8.8. Photoplethysmography -- Problems -- References -- 9. Measurements Of The Respiratory System / Frank P. Primiano Jr. -- 9.1. Modeling the Respiratory System -- 9.2. Measurement of Pressure -- 9.3. Measurement of Gas Flow -- 9.4. Lung Volume -- 9.5. Respiratory Plethysmography -- 9.6. Some Tests of Respiratory Mechanics -- 9.7. Measurement of Gas Concentration -- 9.8. Some Tests of Gas Transport -- Problems -- References -- 10. Chemical Biosensors / Robert A. Peura -- 10.1. Blood-Gas and Acid-Base Physiology -- 10.2. Electrochemical Sensors -- 10.3. Chemical Fibrosensors -- 10.4. Ion-Sensitive Field-Effect Transistor (ISFET) -- 10.5. Immunologically Sensitive Field-Effect Transistor (IMFET) -- 10.6. Noninvasive Blood-Gas Monitoring -- 10.7. Blood-Glucose Sensors -- 10.8. Electronic Noses -- 10.9. Lab-on-a-chip -- 10.10. Summary -- Problems -- References -- 11. Clinical Laboratory Instrumentation / Lawrence A. Wheeler -- 11.1. Spectrophotometry -- 11.2. Automated Chemical Analyzers -- 11.3. Chromatology -- 11.4. Electrophoresis -- 11.5. Hematology -- Problems -- References -- 12. Medical Imaging Systems / Melvin p. Siedband -- 12.1. Information Content of an Image -- 12.2. Modulation Transfer Function -- 12.3. Noise-Equivalent Bandwidth -- 12.4. Image Processing -- 12.5. Radiography -- 12.6. Computed Radiography -- 12.7. Computed Tomography -- 12.8. Magnetic Resonance Imaging -- 12.9. Nuclear Medicine -- 12.10. Single-Photon Emission Computed Tomography -- 12.11. Positron Emission Tomography -- 12.12. Ultrasonography -- 12.13. Contrast Agents -- Problems -- References -- 13. Therapeutic And Prosthetic Devices / Michael R. Neuman -- 13.1. Cardiac Pacemakers and Other Electric Stimulators -- 13.2. Defibrillators and Cardioverters -- 13.3. Mechanical Cardiovascular Orthotic and Prosthetic Devices -- 13.4. Hemodialysis -- 13.5. Lithotripsy -- 13.6. Ventilators -- 13.7. Infant Incubators -- 13.8. Drug Delivery Devices -- 13.9. Surgical Instruments -- 13.10. Therapeutic Applications of the Laser -- Problems -- References -- 14. Electrical Safety / Walter H. Olson -- 14.1. Physiological Effects of Electricity -- 14.2. Important Susceptibility Parameters -- 14.3. Distribution of Electric Power -- 14.4. Macroshock Hazards -- 14.5. Microshock Hazards -- 14.6. Electrical-Safety Codes and Standards -- 14.7. Basic Approaches to Protection Against Shock -- 14.8. Protection: Power Distribution -- 14.9. Protection: Equipment Design -- 14.10. Electrical-Safety Analyzers -- 14.11. Testing the Electric System -- 14.12. Tests of Electric Appliances -- 14.13. Conclusion -- Problems -- References -- APPENDIX -- A.1. Physical Constants -- A.2. International System of Units (SI) Prefixes -- A.3. International System of Units -- A.4. Abbreviations -- A.5. Chemical Elements.

"This book provides biomedical engineers with the premiere reference on medical instrumentation as well as a comprehensive overview of the basic concepts. The revised edition features new material on infant apnea monitors, impedance pneumography, the design of cardiac pacemakers, and disposable defibrillator electrodes and their standards. Each chapter includes new problems and updated reference material that cover the latest medical technologies. The chapters have also been revised with new material in medical imaging, providing biomedical engineers with the most current techniques in the field. This well-established text describes the principles, applications and design of the medical instrumentation most commonly used in hospitals. Because equipment changes with time, the authors stress fundamental principles of operation and general types of equipment. Design principles are emphasized so that a scientist with only some background in electronics can gain enough information to design instruments that may not be commercially available"-- Provided by publisher.