Includes bibliographical references and index.

CNS Demyelinating Disease (Cases 1-21) --- Case 1 A Woman With Subacute Painful Vision Loss --- Case 2 Rapidly Progressive Numbness and Weakness After Soft-Tissue Abscess --- Case 3 Weakness With Neck Flexion --- Case 4 New-Onset Right-Sided Numbness and Double Vision --- Case 5 Progressive Left Lower Extremity Weakness and Thoracic Spinal Cord Lesion --- Case 6 Progressive Spasticity With a Single Magnetic Resonance Imaging Lesion --- Case 7 Fluctuating Vision Loss, Seizures, and Left Parieto-Occipital Mass --- Case 8 Diffuse Pain and Abnormal Brain MRI Findings --- Case 9 Lesions Found by Chance --- Case 10 Encephalopathy and Quadriparesis After an Upper Respiratory Tract Infection --- Case 11 Severe Monocular Vision Loss Followed by Gait Difficulty --- Case 12 Multiple Sclerosis and Cognitive Impairment --- Case 13 New-Onset Gait Difficulty With Kappa Free Light Chains in Cerebrospinal Fluid --- Case 14 A Girl With Back Pain, Paresthesias, and Painful Vision Loss --- Case 15 A Septuagenarian With Progressive Hemiparesis --- Case 16 Recurrent Demyelinating Episodes --- Case 17 Breakthrough Disease While on Multiple Sclerosis Immunomodulatory Therapy --- Case 18 Highly Active Multiple Sclerosis --- Case 19 Progressive Gait Difficulties --- Case 20 Progressive Cerebellar Ataxia After Natalizumab Treatment --- Case 21 Weakness and Dysarthria After Radiosurgery --- Autoimmune Neurologic Disorders (Cases 22-52) --- Case 22 Fatigue, Blurry Vision, and Swollen Optic Nerves --- Case 23 Progressive, Symmetrical, Painless Visual Loss in an Elderly Woman --- Case 24 Personality Changes, Cognitive Decline, and Jerking Movements --- Case 25 Rapidly Progressive Memory Loss, Mood Change, Mutism, and Abnormal Movements --- Case 26 Behavioral and Cognitive Changes Followed by Coma --- Case 27 Episodic Hemiparesis, Cognitive Decline, and Seizures in a Woman With Pernicious Anemia --- Case 28 Rapidly Progressive Dementia and Thyroid Antibodies --- Case 29 Goosebumps and Memory Loss --- Case 30 A Patient With Headache and Progressive Tremor --- Case 31 A Man With Flulike Symptoms and Hemorrhagic Brain Lesions --- Case 32 Hearing Loss, Imbalance, and Diplopia in a 44-Year-Old Man --- Case 33 Chorea, Ataxia, and Disturbed Sleep --- Case 34 Rapidly Progressive Gait and Coordination Difficulties --- Case 35 Dancelike Movements in a Patient With a History of Rash --- Case 36 Body Spasms in a Woman With Thyroid Disease --- Case 37 Stiffness, Spasms, and Frequent Falls in a 41-Year-Old Man --- Case 38 Rapid-Onset Weakness and Numbness in a Patient With Systemic Lupus Erythematosus --- Case 39 Progressive Quadriparesis and Cancer --- Case 40 Progressive Numbness, Burning Pain, Imbalance, and Dryness --- Case 41 Ascending Painful Paresthesias, Progressive Ataxia, and Bilateral Foot Drop --- Case 42 Painless, Symmetric, Ascending Weakness and Sensory Loss --- Case 43 Difficult-to-Treat Polyradiculoneuropathy --- Case 44 Autoimmune Peripheral Nervous System Hyperexcitability --- Case 45 Orthostatism, Constipation, and Early Satiety --- Case 46 Constipation and Syncope --- Case 47 Bulbar-Predominant Weakness --- Case 48 Difficulty Climbing the Stairs --- Case 49 Rapidly Progressive Proximal Weakness --- Case 50 Progressive Weakness and Rash --- Case 51 "Restlessness" After Cancer Diagnosis and Treatment --- Case 52 Sudden Onset of Diplopia and a Skeletal Muscle Antibody --- Other Inflammatory CNS Disorders and Neuroimmunologic Mimics (Cases 53-83) --- Case 53 Diplopia, Orbital Pain, and Vision Loss in a Middle-Aged Woman --- Case 54 A Young Man With Visual Field Loss, Decreased Hearing, and Confusion --- Case 55 A Woman With Progressive Gait Difficulty and White Matter Abnormalities --- Case 56 Progressive Asymmetrical Limb Impairment and Cognitive Decline With Leukoencephalopathy --- Case 57 A Woman With Fever, Confusion, and Seizures --- Case 58 Encephalopathy With Alternating Hemispheric MRI Abnormalities --- Case 59 Rapid-Onset Hemibody Sensory Loss, Incoordination, and Muscle Jerking --- Case 60 A History of Sarcoidosis and a New Brain Lesion --- Case 61 Headache and Hemiparesis in Middle Age --- Case 62 Subacute Cognitive Decline in an 86-Year-Old Woman With Prior Lobar Intracerebral Hemorrhage --- Case 63 A 75-Year-Old Man With 5 Days of Progressive Gait Difficulties and Confusion --- Case 64 Night Sweats and Paraparesis --- Case 65 A Woman With Headaches and a Tumefactive Brain Lesion --- Case 66 Behavioral Change, Seizures, and Temporal Lobe Lesion --- Case 67 A Young Woman With Vessel Dissection and Brainstem Lesions --- Case 68 Headache, Uveitis, and Leptomeningeal Enhancement --- Case 69 Weakness and Punctate Enhancement --- Case 70 Bilateral Paresthesias in Crohn Disease --- Case 71 Seizures and Enhancing Brain Lesions --- Case 72 A Man With Recurrent Headache and Focal Neurologic Deficits --- Case 73 Headache, Radicular Pain, and Enhancing Lesions --- Case 74 Seizures 3 Months After Endarterectomy --- Case 75 Progressive Bilateral Arm Pain, Gait Disturbance, Constipation, and Urinary Retention --- Case 76 A Woman With Subacute Numbness of the Trunk, Arms, and Legs --- Case 77 A Septuagenarian With Progressive Lower Extremity Weakness and Pain --- Case 78 Acute Quadriparesis in a Smoker --- Case 79 A 25-Year-Old Man With Recurrent Back Pain and Rapid-Onset Paraplegia --- Case 80 Progressive Myelopathy After Neck Pain --- Case 81 Progressive Imbalance and Visual Impairment in a Patient With Diabetes --- Case 82 Progressive Myelopathy After Spine Surgery --- Case 83 Altered Mental Status During the COVID-19 Pandemic --- Questions and Answers